Genotypes and phenotypes of patients with Lafora disease living in Germany

Background: LaFora progressive myoclonus epilepsy (LaFora disease) is usually time-onset, fatal neurodegenerative disease caused by a mutation rare biallelic in EPM2A (Laforin) or EPM2B (NHLRC1, Malin). LaFora disease epidemiology in Germany largely unknown. The aim of this retrospective case series was to characterize genotypes and phenotypes of patients with diseases LaFora living in Germany.


Methods: The patient described in this case a series of an initial clinical diagnosis is suspected LaFora disease, or unclassified progressive myoclonus epilepsy. Molecular genetic diagnostics, including next generation sequencing-based diagnostic panel analysis or whole exome sequencing is done.


Results: Parents of four of the 11 patients nonconsanguineous and German origin, while other patients have parents relatives. Various variants found in EPM2A (six patients) and in EPM2B (five patients). Eight variants have not been reported in the literature so far. The patients bearing a new variant has a typical onset during adolescence and show classic disease course.


Conclusion: This is the first case of a larger series of patients LaFora in Germany. Our data allows real LaFora prevalence estimates in Germany for 1.69 per 10 million people. wider application of gene panels or whole exome diagnostics help clarify unclassified progressive myoclonus epilepsy and establish an early diagnosis, which will become more important as a causal therapy approaches have been developed and will soon be tested in a phase I study


EPM2A has been certified as the causative gene in patients with LaFora disease (LD), which is an autosomal recessive rare and severe form of progressive myoclonus epilepsy. The classic LD begins in adolescence, characterized by various types of seizures with myoclonic seizures as main types. Usually within 10 years, harsh seizures, fast developing dementia and vegetative state is present. LD especially common in Mediterranean countries.

Here, we report the Chinese family with a new compound heterozygous mutations in the genes EPM2A, characterized by recurrent vomiting, intractable epilepsy, and progressive cognitive decline.

 Genotypes and phenotypes of patients with Lafora disease living in Germany
Genotypes and phenotypes of patients with Lafora disease living in Germany

brain proton magnetic resonance spectroscopy findings in Beagle dogs with genetically confirmed LaFora disease.

have identified cortical atrophy using magnetic resonance imaging (MRI) in humans and dogs with LaFora disease (LD). In humans, proton magnetic resonance spectroscopy (1HMRS) of the brain indicating a drop of N-acetyl-aspartate (NAA) relative to other brain metabolites. 1HMRS brain findings in dogs with LD less.

A 6 year old Beagle woman presented with a history of general tonic-clonic seizures, and myoclonus reflex single episodic. Clinical, hematological, and neurological examination findings and 3-Tesla MRI of the brain that is mediocre. 1HMRS brain with voxel position in the thalamus do in Beagle affected.

ETC-1002

A8710-25 25 mg
EUR 1730.4
Description: ETC-1002 is an oral ACL inhibitor (IC50= 29 ?M) and AMPK activator. In vitro, ETC-1002 increased levels of AMP-activated protein kinase (AMPK) phosphorylation, reduced activity of MAP kinases and decreased production of proinflammatory cytokines and chemokines.

ETC-1002

A8710-5 5 mg
EUR 616.8
Description: ETC-1002 is an oral ACL inhibitor (IC50= 29 ?M) and AMPK activator. In vitro, ETC-1002 increased levels of AMP-activated protein kinase (AMPK) phosphorylation, reduced activity of MAP kinases and decreased production of proinflammatory cytokines and chemokines.

ETC-206

HY-112424 10mM/1mL
EUR 392.4

ETC-159

HY-18988 10mM/1mL
EUR 135.6

Cas9 Protein and T7 gRNA SmartNuclease Synthesis Kit

CAS400A-KIT 1 kit (10 rxn)
EUR 1332

Cas9 Protein and T7 gRNA SmartNuclease Synthesis Kit

CAS410A-KIT 1 kit (10 rxn)
EUR 798

Cas9-EGFP Protein and T7 gRNA SmartNuclease Synthesis Kit

CAS420A-KIT 1 kit (10 rxn)
EUR 828

LeafEye Colorimeter for leaf, petal, etc.

TBD-4 each Ask for price
Description: The LeafEye Colorimeter for leaf, petal, etc. is available in Europe and for worldwide shipping via Gentaur.

ELISA kit for Sheep Brucella Antibody

KTE110086-48T 48T
EUR 424.8
Description: Quantitative sandwich ELISA for measuring Sheep Brucella Antibody in samples from cell culture supernatants, serum, whole blood, plasma and other biological fluids.

ELISA kit for Sheep Brucella Antibody

KTE110086-5platesof96wells 5 plates of 96 wells
EUR 2702.4
Description: Quantitative sandwich ELISA for measuring Sheep Brucella Antibody in samples from cell culture supernatants, serum, whole blood, plasma and other biological fluids.

ELISA kit for Sheep Brucella Antibody

KTE110086-96T 96T
EUR 686.4
Description: Quantitative sandwich ELISA for measuring Sheep Brucella Antibody in samples from cell culture supernatants, serum, whole blood, plasma and other biological fluids.

Glucagon Like Peptide 1 (GLP1) Polyclonal Antibody (Human, Mouse, Rat, Guinea pig, Dog, Pig, Bovine, Sheep)

4-PAA804Mi01
  • EUR 283.20
  • EUR 2805.60
  • EUR 703.20
  • EUR 352.80
  • EUR 250.80
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Rabbit polyclonal antibody against Human, Mouse, Rat, Guinea pig, Dog, Pig, Bovine, Sheep Glucagon Like Peptide 1 (GLP1)

ELISA kit for Sheep Brucella  Kit

KTE110085-48T 48T
EUR 424.8
Description: Quantitative sandwich ELISA for measuring Sheep Brucella  Kit in samples from cell culture supernatants, serum, whole blood, plasma and other biological fluids.

ELISA kit for Sheep Brucella  Kit

KTE110085-5platesof96wells 5 plates of 96 wells
EUR 2702.4
Description: Quantitative sandwich ELISA for measuring Sheep Brucella  Kit in samples from cell culture supernatants, serum, whole blood, plasma and other biological fluids.

ELISA kit for Sheep Brucella  Kit

KTE110085-96T 96T
EUR 686.4
Description: Quantitative sandwich ELISA for measuring Sheep Brucella  Kit in samples from cell culture supernatants, serum, whole blood, plasma and other biological fluids.

Glucagon Like Peptide 1 (GLP1) Polyclonal Antibody (Human, Mouse, Rat, Guinea pig, Dog, Pig, Bovine, Sheep), APC

4-PAA804Mi01-APC
  • EUR 394.80
  • EUR 3649.20
  • EUR 1024.80
  • EUR 499.20
  • EUR 254.40
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Rabbit polyclonal antibody against Human, Mouse, Rat, Guinea pig, Dog, Pig, Bovine, Sheep Glucagon Like Peptide 1 (GLP1). This antibody is labeled with APC.

Glucagon Like Peptide 1 (GLP1) Polyclonal Antibody (Human, Mouse, Rat, Guinea pig, Dog, Pig, Bovine, Sheep), Biotinylated

4-PAA804Mi01-Biotin
  • EUR 358.80
  • EUR 2745.60
  • EUR 820.80
  • EUR 435.60
  • EUR 256.80
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Rabbit polyclonal antibody against Human, Mouse, Rat, Guinea pig, Dog, Pig, Bovine, Sheep Glucagon Like Peptide 1 (GLP1). This antibody is labeled with Biotin.

Glucagon Like Peptide 1 (GLP1) Polyclonal Antibody (Human, Mouse, Rat, Guinea pig, Dog, Pig, Bovine, Sheep), Cy3

4-PAA804Mi01-Cy3
  • EUR 476.40
  • EUR 4815.60
  • EUR 1316.40
  • EUR 615.60
  • EUR 289.20
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Rabbit polyclonal antibody against Human, Mouse, Rat, Guinea pig, Dog, Pig, Bovine, Sheep Glucagon Like Peptide 1 (GLP1). This antibody is labeled with Cy3.

Glucagon Like Peptide 1 (GLP1) Polyclonal Antibody (Human, Mouse, Rat, Guinea pig, Dog, Pig, Bovine, Sheep), FITC

4-PAA804Mi01-FITC
  • EUR 339.60
  • EUR 2942.40
  • EUR 843.60
  • EUR 423.60
  • EUR 226.80
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Rabbit polyclonal antibody against Human, Mouse, Rat, Guinea pig, Dog, Pig, Bovine, Sheep Glucagon Like Peptide 1 (GLP1). This antibody is labeled with FITC.

Glucagon Like Peptide 1 (GLP1) Polyclonal Antibody (Human, Mouse, Rat, Guinea pig, Dog, Pig, Bovine, Sheep), HRP

4-PAA804Mi01-HRP
  • EUR 362.40
  • EUR 3182.40
  • EUR 907.20
  • EUR 452.40
  • EUR 240.00
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Rabbit polyclonal antibody against Human, Mouse, Rat, Guinea pig, Dog, Pig, Bovine, Sheep Glucagon Like Peptide 1 (GLP1). This antibody is labeled with HRP.

Glucagon Like Peptide 1 (GLP1) Polyclonal Antibody (Human, Mouse, Rat, Guinea pig, Dog, Pig, Bovine, Sheep), PE

4-PAA804Mi01-PE
  • EUR 339.60
  • EUR 2942.40
  • EUR 843.60
  • EUR 423.60
  • EUR 226.80
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Rabbit polyclonal antibody against Human, Mouse, Rat, Guinea pig, Dog, Pig, Bovine, Sheep Glucagon Like Peptide 1 (GLP1). This antibody is labeled with PE.

Tween-20 (100%, undiluted) for ELISA, Western, IP etc

TW-100100 500 ml
EUR 139.2

Holder for Plasmid Midi, Maxi and Maxi plus, Ion Exchange column

FAPDE-holder-for-ion-exchange 1 prep
EUR 189.6

ELISA kit for Sheep Antibody against Foot and Mouth Disease IgM (FMDV-IgM)

KTE110058-48T 48T
EUR 398.4
Description: Quantitative sandwich ELISA for measuring Sheep Antibody against Foot and Mouth Disease IgM (FMDV-IgM) in samples from cell culture supernatants, serum, whole blood, plasma and other biological fluids.

ELISA kit for Sheep Antibody against Foot and Mouth Disease IgM (FMDV-IgM)

KTE110058-5platesof96wells 5 plates of 96 wells
EUR 2538
Description: Quantitative sandwich ELISA for measuring Sheep Antibody against Foot and Mouth Disease IgM (FMDV-IgM) in samples from cell culture supernatants, serum, whole blood, plasma and other biological fluids.

ELISA kit for Sheep Antibody against Foot and Mouth Disease IgM (FMDV-IgM)

KTE110058-96T 96T
EUR 646.8
Description: Quantitative sandwich ELISA for measuring Sheep Antibody against Foot and Mouth Disease IgM (FMDV-IgM) in samples from cell culture supernatants, serum, whole blood, plasma and other biological fluids.

Cas9 SmartNuclease Extra Ligation Kit [includes 5x ligation buffer (10 ul) and Fast ligase (2.5ul)]

CAS9LIG-KIT 1 Kit
EUR 183.6

ELISA kit for Bovine tetanus antibody

EK0020 96 tests
EUR 854.4
Description: Enzyme-linked immunosorbent assay kit for quantification of Bovine tetanus antibody in samples from serum, plasma, tissue homogenates and other biological fluids.

ELISA kit for Bovine Brucella Antibody

KTE10440-48T 48T
EUR 424.8
Description: Quantitative sandwich ELISA for measuring Bovine Brucella Antibody in samples from cell culture supernatants, serum, whole blood, plasma and other biological fluids.

ELISA kit for Bovine Brucella Antibody

KTE10440-5platesof96wells 5 plates of 96 wells
EUR 2702.4
Description: Quantitative sandwich ELISA for measuring Bovine Brucella Antibody in samples from cell culture supernatants, serum, whole blood, plasma and other biological fluids.

ELISA kit for Bovine Brucella Antibody

KTE10440-96T 96T
EUR 686.4
Description: Quantitative sandwich ELISA for measuring Bovine Brucella Antibody in samples from cell culture supernatants, serum, whole blood, plasma and other biological fluids.

ELISA kit for Bovine Theileria Antibody

KTE10448-48T 48T
EUR 424.8
Description: Quantitative sandwich ELISA for measuring Bovine Theileria Antibody in samples from cell culture supernatants, serum, whole blood, plasma and other biological fluids.

ELISA kit for Bovine Theileria Antibody

KTE10448-5platesof96wells 5 plates of 96 wells
EUR 2702.4
Description: Quantitative sandwich ELISA for measuring Bovine Theileria Antibody in samples from cell culture supernatants, serum, whole blood, plasma and other biological fluids.

ELISA kit for Bovine Theileria Antibody

KTE10448-96T 96T
EUR 686.4
Description: Quantitative sandwich ELISA for measuring Bovine Theileria Antibody in samples from cell culture supernatants, serum, whole blood, plasma and other biological fluids.

Glucagon Like Peptide 1 (GLP1) Polyclonal Antibody (Human, Mouse, Rat, Guinea pig, Dog, Pig, Bovine, Sheep), APC-Cy7

4-PAA804Mi01-APC-Cy7
  • EUR 645.60
  • EUR 7154.40
  • EUR 1905.60
  • EUR 855.60
  • EUR 364.80
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Rabbit polyclonal antibody against Human, Mouse, Rat, Guinea pig, Dog, Pig, Bovine, Sheep Glucagon Like Peptide 1 (GLP1). This antibody is labeled with APC-Cy7.

Sheep anti-Dog IgG2 Antibody

abx401276-1mg 1 mg
EUR 444

ELISA kit for Sheep GHRL (Ghrelin)

ELK7969 1 plate of 96 wells
EUR 631.2
Description: A competitive Inhibition ELISA kit for detection of Ghrelin from Sheep in samples from blood, serum, plasma, cell culture fluid and other biological fluids.

ELISA kit for Sheep PRL (Prolactin)

ELK8303 1 plate of 96 wells
EUR 631.2
Description: A sandwich ELISA kit for detection of Prolactin from Sheep in samples from blood, serum, plasma, cell culture fluid and other biological fluids.

ELISA kit for Sheep RETN (Resistin)

ELK8305 1 plate of 96 wells
EUR 631.2
Description: A sandwich ELISA kit for detection of Resistin from Sheep in samples from blood, serum, plasma, cell culture fluid and other biological fluids.

ELISA kit for Sheep Clusterin (CLU)

EK0433 96 tests
EUR 854.4
Description: Enzyme-linked immunosorbent assay kit for quantification of Sheep Clusterin (CLU) in samples from serum, plasma, tissue homogenates and other biological fluids.

ELISA kit for Sheep Osteopontin (SPP1)

KTE110006-48T 48T
EUR 424.8
Description: Quantitative sandwich ELISA for measuring Sheep Osteopontin (SPP1) in samples from cell culture supernatants, serum, whole blood, plasma and other biological fluids.

ELISA kit for Sheep Osteopontin (SPP1)

KTE110006-5platesof96wells 5 plates of 96 wells
EUR 2702.4
Description: Quantitative sandwich ELISA for measuring Sheep Osteopontin (SPP1) in samples from cell culture supernatants, serum, whole blood, plasma and other biological fluids.

ELISA kit for Sheep Osteopontin (SPP1)

KTE110006-96T 96T
EUR 686.4
Description: Quantitative sandwich ELISA for measuring Sheep Osteopontin (SPP1) in samples from cell culture supernatants, serum, whole blood, plasma and other biological fluids.

ELISA kit for Sheep Progesterone (PROG)

KTE110019-48T 48T
EUR 438
Description: Quantitative sandwich ELISA for measuring Sheep Progesterone (PROG) in samples from cell culture supernatants, serum, whole blood, plasma and other biological fluids.

ELISA kit for Sheep Progesterone (PROG)

KTE110019-5platesof96wells 5 plates of 96 wells
EUR 3030
Description: Quantitative sandwich ELISA for measuring Sheep Progesterone (PROG) in samples from cell culture supernatants, serum, whole blood, plasma and other biological fluids.

ELISA kit for Sheep Progesterone (PROG)

KTE110019-96T 96T
EUR 764.4
Description: Quantitative sandwich ELISA for measuring Sheep Progesterone (PROG) in samples from cell culture supernatants, serum, whole blood, plasma and other biological fluids.

ELISA kit for Sheep Prolactin (PRL)

KTE110024-48T 48T
EUR 424.8
Description: Quantitative sandwich ELISA for measuring Sheep Prolactin (PRL) in samples from cell culture supernatants, serum, whole blood, plasma and other biological fluids.

ELISA kit for Sheep Prolactin (PRL)

KTE110024-5platesof96wells 5 plates of 96 wells
EUR 2702.4
Description: Quantitative sandwich ELISA for measuring Sheep Prolactin (PRL) in samples from cell culture supernatants, serum, whole blood, plasma and other biological fluids.

ELISA kit for Sheep Prolactin (PRL)

KTE110024-96T 96T
EUR 686.4
Description: Quantitative sandwich ELISA for measuring Sheep Prolactin (PRL) in samples from cell culture supernatants, serum, whole blood, plasma and other biological fluids.

ELISA kit for Sheep Plasminogen (PLG)

KTE110026-48T 48T
EUR 424.8
Description: Quantitative sandwich ELISA for measuring Sheep Plasminogen (PLG) in samples from cell culture supernatants, serum, whole blood, plasma and other biological fluids.

ELISA kit for Sheep Plasminogen (PLG)

KTE110026-5platesof96wells 5 plates of 96 wells
EUR 2702.4
Description: Quantitative sandwich ELISA for measuring Sheep Plasminogen (PLG) in samples from cell culture supernatants, serum, whole blood, plasma and other biological fluids.

ELISA kit for Sheep Plasminogen (PLG)

KTE110026-96T 96T
EUR 686.4
Description: Quantitative sandwich ELISA for measuring Sheep Plasminogen (PLG) in samples from cell culture supernatants, serum, whole blood, plasma and other biological fluids.

ELISA kit for Sheep Melatonin (MT)

KTE110040-48T 48T
EUR 424.8
Description: Quantitative sandwich ELISA for measuring Sheep Melatonin (MT) in samples from cell culture supernatants, serum, whole blood, plasma and other biological fluids.

ELISA kit for Sheep Melatonin (MT)

KTE110040-5platesof96wells 5 plates of 96 wells
EUR 2702.4
Description: Quantitative sandwich ELISA for measuring Sheep Melatonin (MT) in samples from cell culture supernatants, serum, whole blood, plasma and other biological fluids.

ELISA kit for Sheep Melatonin (MT)

KTE110040-96T 96T
EUR 686.4
Description: Quantitative sandwich ELISA for measuring Sheep Melatonin (MT) in samples from cell culture supernatants, serum, whole blood, plasma and other biological fluids.

ELISA kit for Sheep Myoglobin (MB)

KTE110046-48T 48T
EUR 424.8
Description: Quantitative sandwich ELISA for measuring Sheep Myoglobin (MB) in samples from cell culture supernatants, serum, whole blood, plasma and other biological fluids.

ELISA kit for Sheep Myoglobin (MB)

KTE110046-5platesof96wells 5 plates of 96 wells
EUR 2702.4
Description: Quantitative sandwich ELISA for measuring Sheep Myoglobin (MB) in samples from cell culture supernatants, serum, whole blood, plasma and other biological fluids.

ELISA kit for Sheep Myoglobin (MB)

KTE110046-96T 96T
EUR 686.4
Description: Quantitative sandwich ELISA for measuring Sheep Myoglobin (MB) in samples from cell culture supernatants, serum, whole blood, plasma and other biological fluids.

ELISA kit for Sheep Leptin (LEP)

KTE110050-48T 48T
EUR 424.8
Description: Quantitative sandwich ELISA for measuring Sheep Leptin (LEP) in samples from cell culture supernatants, serum, whole blood, plasma and other biological fluids.

ELISA kit for Sheep Leptin (LEP)

KTE110050-5platesof96wells 5 plates of 96 wells
EUR 2702.4
Description: Quantitative sandwich ELISA for measuring Sheep Leptin (LEP) in samples from cell culture supernatants, serum, whole blood, plasma and other biological fluids.

ELISA kit for Sheep Leptin (LEP)

KTE110050-96T 96T
EUR 686.4
Description: Quantitative sandwich ELISA for measuring Sheep Leptin (LEP) in samples from cell culture supernatants, serum, whole blood, plasma and other biological fluids.

ELISA kit for Sheep Dihydrotestosterone (DHT)

KTE110051-48T 48T
EUR 424.8
Description: Quantitative sandwich ELISA for measuring Sheep Dihydrotestosterone (DHT) in samples from cell culture supernatants, serum, whole blood, plasma and other biological fluids.

ELISA kit for Sheep Dihydrotestosterone (DHT)

KTE110051-5platesof96wells 5 plates of 96 wells
EUR 2702.4
Description: Quantitative sandwich ELISA for measuring Sheep Dihydrotestosterone (DHT) in samples from cell culture supernatants, serum, whole blood, plasma and other biological fluids.

ELISA kit for Sheep Dihydrotestosterone (DHT)

KTE110051-96T 96T
EUR 686.4
Description: Quantitative sandwich ELISA for measuring Sheep Dihydrotestosterone (DHT) in samples from cell culture supernatants, serum, whole blood, plasma and other biological fluids.

ELISA kit for Sheep Decorin (DCN)

KTE110052-48T 48T
EUR 424.8
Description: Quantitative sandwich ELISA for measuring Sheep Decorin (DCN) in samples from cell culture supernatants, serum, whole blood, plasma and other biological fluids.

ELISA kit for Sheep Decorin (DCN)

KTE110052-5platesof96wells 5 plates of 96 wells
EUR 2702.4
Description: Quantitative sandwich ELISA for measuring Sheep Decorin (DCN) in samples from cell culture supernatants, serum, whole blood, plasma and other biological fluids.

ELISA kit for Sheep Decorin (DCN)

KTE110052-96T 96T
EUR 686.4
Description: Quantitative sandwich ELISA for measuring Sheep Decorin (DCN) in samples from cell culture supernatants, serum, whole blood, plasma and other biological fluids.

ELISA kit for Sheep Haptoglobin (HP)

KTE110063-48T 48T
EUR 424.8
Description: Quantitative sandwich ELISA for measuring Sheep Haptoglobin (HP) in samples from cell culture supernatants, serum, whole blood, plasma and other biological fluids.

ELISA kit for Sheep Haptoglobin (HP)

KTE110063-5platesof96wells 5 plates of 96 wells
EUR 2702.4
Description: Quantitative sandwich ELISA for measuring Sheep Haptoglobin (HP) in samples from cell culture supernatants, serum, whole blood, plasma and other biological fluids.

ELISA kit for Sheep Haptoglobin (HP)

KTE110063-96T 96T
EUR 686.4
Description: Quantitative sandwich ELISA for measuring Sheep Haptoglobin (HP) in samples from cell culture supernatants, serum, whole blood, plasma and other biological fluids.

ELISA kit for Sheep Myeloperoxidase (MPO)

KTE110064-48T 48T
EUR 424.8
Description: Quantitative sandwich ELISA for measuring Sheep Myeloperoxidase (MPO) in samples from cell culture supernatants, serum, whole blood, plasma and other biological fluids.

ELISA kit for Sheep Myeloperoxidase (MPO)

KTE110064-5platesof96wells 5 plates of 96 wells
EUR 2702.4
Description: Quantitative sandwich ELISA for measuring Sheep Myeloperoxidase (MPO) in samples from cell culture supernatants, serum, whole blood, plasma and other biological fluids.

ELISA kit for Sheep Myeloperoxidase (MPO)

KTE110064-96T 96T
EUR 686.4
Description: Quantitative sandwich ELISA for measuring Sheep Myeloperoxidase (MPO) in samples from cell culture supernatants, serum, whole blood, plasma and other biological fluids.

ELISA kit for Sheep Adiponectin (ADIPOQ)

KTE110067-48T 48T
EUR 424.8
Description: Quantitative sandwich ELISA for measuring Sheep Adiponectin (ADIPOQ) in samples from cell culture supernatants, serum, whole blood, plasma and other biological fluids.

ELISA kit for Sheep Adiponectin (ADIPOQ)

KTE110067-5platesof96wells 5 plates of 96 wells
EUR 2702.4
Description: Quantitative sandwich ELISA for measuring Sheep Adiponectin (ADIPOQ) in samples from cell culture supernatants, serum, whole blood, plasma and other biological fluids.

ELISA kit for Sheep Adiponectin (ADIPOQ)

KTE110067-96T 96T
EUR 686.4
Description: Quantitative sandwich ELISA for measuring Sheep Adiponectin (ADIPOQ) in samples from cell culture supernatants, serum, whole blood, plasma and other biological fluids.

ELISA kit for Sheep Thyroxine (T4)

KTE110072-48T 48T
EUR 424.8
Description: Quantitative sandwich ELISA for measuring Sheep Thyroxine (T4) in samples from cell culture supernatants, serum, whole blood, plasma and other biological fluids.

ELISA kit for Sheep Thyroxine (T4)

KTE110072-5platesof96wells 5 plates of 96 wells
EUR 2702.4
Description: Quantitative sandwich ELISA for measuring Sheep Thyroxine (T4) in samples from cell culture supernatants, serum, whole blood, plasma and other biological fluids.

ELISA kit for Sheep Thyroxine (T4)

KTE110072-96T 96T
EUR 686.4
Description: Quantitative sandwich ELISA for measuring Sheep Thyroxine (T4) in samples from cell culture supernatants, serum, whole blood, plasma and other biological fluids.

Sheep anti Bovine IgG1

41R-IS001 1 mg
EUR 289.2
Description: Affinity purified Sheep polyclonal Sheep anti Bovine IgG1 antibody

Sheep anti Bovine IgA

41R-SB001 1 mg
EUR 259.2
Description: Sheep anti Bovine IgA secondary antibody

Sheep anti Bovine IgG1

20R-IS001 1 mg
EUR 289.2
Description: Sheep anti Bovine IgG1 antibody

Sheep anti Bovine IgM

40C-CB0143 1 mg
EUR 243.6
Description: Sheep anti Bovine IgM secondary antibody

OREXIN A AND B ELISA Kit (Sheep) (OKWB00437)

OKWB00437 96 Wells
EUR 686.4
Description: Description of target: ;Species reactivity: Sheep;Application: ;Assay info: Assay Type: Quantitative Sandwich ELISA;Sensitivity: 9.4 pg/mL

ELISA kit for Sheep Albumin (Alb)ELISA Kit

EK0427 96 tests
EUR 794.4
Description: Enzyme-linked immunosorbent assay kit for quantification of Sheep Albumin (Alb)ELISA Kit in samples from serum, plasma, tissue homogenates and other biological fluids.

ELISA kit for Pig Foot and Mouth Disease Virus 3ABC Antibody

KTE80231-48T 48T
EUR 464.4
Description: Quantitative sandwich ELISA for measuring Pig Foot and Mouth Disease Virus 3ABC Antibody in samples from cell culture supernatants, serum, whole blood, plasma and other biological fluids.

ELISA kit for Pig Foot and Mouth Disease Virus 3ABC Antibody

KTE80231-5platesof96wells 5 plates of 96 wells
EUR 3248.4
Description: Quantitative sandwich ELISA for measuring Pig Foot and Mouth Disease Virus 3ABC Antibody in samples from cell culture supernatants, serum, whole blood, plasma and other biological fluids.

ELISA kit for Pig Foot and Mouth Disease Virus 3ABC Antibody

KTE80231-96T 96T
EUR 816
Description: Quantitative sandwich ELISA for measuring Pig Foot and Mouth Disease Virus 3ABC Antibody in samples from cell culture supernatants, serum, whole blood, plasma and other biological fluids.

ELISA kit for Sheep Anti-toxoplasmosis (IgM) Antibody

KTE110059-48T 48T
EUR 424.8
Description: Quantitative sandwich ELISA for measuring Sheep Anti-toxoplasmosis (IgM) Antibody in samples from cell culture supernatants, serum, whole blood, plasma and other biological fluids.

ELISA kit for Sheep Anti-toxoplasmosis (IgM) Antibody

KTE110059-5platesof96wells 5 plates of 96 wells
EUR 2702.4
Description: Quantitative sandwich ELISA for measuring Sheep Anti-toxoplasmosis (IgM) Antibody in samples from cell culture supernatants, serum, whole blood, plasma and other biological fluids.

ELISA kit for Sheep Anti-toxoplasmosis (IgM) Antibody

KTE110059-96T 96T
EUR 686.4
Description: Quantitative sandwich ELISA for measuring Sheep Anti-toxoplasmosis (IgM) Antibody in samples from cell culture supernatants, serum, whole blood, plasma and other biological fluids.

ELISA kit for Bovine Cortisol

EK0010 96 tests
EUR 723.6
Description: Enzyme-linked immunosorbent assay kit for quantification of Bovine Cortisol in samples from serum, plasma, tissue homogenates and other biological fluids.

ELISA kit for Bovine Eotaxin

EK1056 96 tests
EUR 804
Description: Enzyme-linked immunosorbent assay kit for quantification of Bovine Eotaxin in samples from serum, plasma, tissue homogenates and other biological fluids.

ELISA kit for Bovine Erythropoietin

EK1063 96 tests
EUR 804
Description: Enzyme-linked immunosorbent assay kit for quantification of Bovine Erythropoietin in samples from serum, plasma, tissue homogenates and other biological fluids.

ELISA kit for Bovine Fibronectin

EK1087 96 tests
EUR 804
Description: Enzyme-linked immunosorbent assay kit for quantification of Bovine Fibronectin in samples from serum, plasma, tissue homogenates and other biological fluids.

ELISA kit for Bovine Somatotropin

EK1097 96 tests
EUR 804
Description: Enzyme-linked immunosorbent assay kit for quantification of Bovine Somatotropin in samples from serum, plasma, tissue homogenates and other biological fluids.

ELISA kit for Bovine Lactoperoxidase

EK1604 96 tests
EUR 804
Description: Enzyme-linked immunosorbent assay kit for quantification of Bovine Lactoperoxidase in samples from serum, plasma, tissue homogenates and other biological fluids.

ELISA kit for Bovine Prothrombin

EK2161 96 tests
EUR 804
Description: Enzyme-linked immunosorbent assay kit for quantification of Bovine Prothrombin in samples from serum, plasma, tissue homogenates and other biological fluids.

ELISA kit for Bovine Lactotransferrin

EK2242 96 tests
EUR 804
Description: Enzyme-linked immunosorbent assay kit for quantification of Bovine Lactotransferrin in samples from serum, plasma, tissue homogenates and other biological fluids.

ELISA kit for Bovine Haptoglobin

EK2287 96 tests
EUR 804
Description: Enzyme-linked immunosorbent assay kit for quantification of Bovine Haptoglobin in samples from serum, plasma, tissue homogenates and other biological fluids.

ELISA kit for Bovine Prolactin

EK2345 96 tests
EUR 400.8
Description: Enzyme-linked immunosorbent assay kit for quantification of Bovine Prolactin in samples from serum, plasma, tissue homogenates and other biological fluids.

ELISA kit for Bovine Enteropeptidase

EK3060 96 tests
EUR 804
Description: Enzyme-linked immunosorbent assay kit for quantification of Bovine Enteropeptidase in samples from serum, plasma, tissue homogenates and other biological fluids.

ELISA kit for Bovine Rhodopsin

EK3609 96 tests
EUR 804
Description: Enzyme-linked immunosorbent assay kit for quantification of Bovine Rhodopsin in samples from serum, plasma, tissue homogenates and other biological fluids.

ELISA kit for Bovine Lactadherin

EK4502 96 tests
EUR 804
Description: Enzyme-linked immunosorbent assay kit for quantification of Bovine Lactadherin in samples from serum, plasma, tissue homogenates and other biological fluids.

ELISA kit for Bovine Decorin

EK4718 96 tests
EUR 804
Description: Enzyme-linked immunosorbent assay kit for quantification of Bovine Decorin in samples from serum, plasma, tissue homogenates and other biological fluids.

ELISA kit for Bovine Cholinesterase

EK4849 96 tests
EUR 804
Description: Enzyme-linked immunosorbent assay kit for quantification of Bovine Cholinesterase in samples from serum, plasma, tissue homogenates and other biological fluids.

ELISA kit for Bovine Insulin

EK5089 96 tests
EUR 804
Description: Enzyme-linked immunosorbent assay kit for quantification of Bovine Insulin in samples from serum, plasma, tissue homogenates and other biological fluids.

ELISA kit for Bovine Herpesvirus

KTE10438-48T 48T
EUR 424.8
Description: Quantitative sandwich ELISA for measuring Bovine Herpesvirus in samples from cell culture supernatants, serum, whole blood, plasma and other biological fluids.

ELISA kit for Bovine Herpesvirus

KTE10438-5platesof96wells 5 plates of 96 wells
EUR 2702.4
Description: Quantitative sandwich ELISA for measuring Bovine Herpesvirus in samples from cell culture supernatants, serum, whole blood, plasma and other biological fluids.

ELISA kit for Bovine Herpesvirus

KTE10438-96T 96T
EUR 686.4
Description: Quantitative sandwich ELISA for measuring Bovine Herpesvirus in samples from cell culture supernatants, serum, whole blood, plasma and other biological fluids.

ELISA kit for Bovine Estrogen

KTE10439-48T 48T
EUR 424.8
Description: Quantitative sandwich ELISA for measuring Bovine Estrogen in samples from cell culture supernatants, serum, whole blood, plasma and other biological fluids.

ELISA kit for Bovine Estrogen

KTE10439-5platesof96wells 5 plates of 96 wells
EUR 2702.4
Description: Quantitative sandwich ELISA for measuring Bovine Estrogen in samples from cell culture supernatants, serum, whole blood, plasma and other biological fluids.

ELISA kit for Bovine Estrogen

KTE10439-96T 96T
EUR 686.4
Description: Quantitative sandwich ELISA for measuring Bovine Estrogen in samples from cell culture supernatants, serum, whole blood, plasma and other biological fluids.

ELISA kit for Bovine Neospora

KTE10452-48T 48T
EUR 424.8
Description: Quantitative sandwich ELISA for measuring Bovine Neospora in samples from cell culture supernatants, serum, whole blood, plasma and other biological fluids.

ELISA kit for Bovine Neospora

KTE10452-5platesof96wells 5 plates of 96 wells
EUR 2702.4
Description: Quantitative sandwich ELISA for measuring Bovine Neospora in samples from cell culture supernatants, serum, whole blood, plasma and other biological fluids.

ELISA kit for Bovine Neospora

KTE10452-96T 96T
EUR 686.4
Description: Quantitative sandwich ELISA for measuring Bovine Neospora in samples from cell culture supernatants, serum, whole blood, plasma and other biological fluids.

ELISA kit for Bovine Rabies

KTE10462-48T 48T
EUR 424.8
Description: Quantitative sandwich ELISA for measuring Bovine Rabies in samples from cell culture supernatants, serum, whole blood, plasma and other biological fluids.

ELISA kit for Bovine Rabies

KTE10462-5platesof96wells 5 plates of 96 wells
EUR 2702.4
Description: Quantitative sandwich ELISA for measuring Bovine Rabies in samples from cell culture supernatants, serum, whole blood, plasma and other biological fluids.

ELISA kit for Bovine Rabies

KTE10462-96T 96T
EUR 686.4
Description: Quantitative sandwich ELISA for measuring Bovine Rabies in samples from cell culture supernatants, serum, whole blood, plasma and other biological fluids.

ELISA kit for Bovine Leptospiriosis

KTE10463-48T 48T
EUR 424.8
Description: Quantitative sandwich ELISA for measuring Bovine Leptospiriosis in samples from cell culture supernatants, serum, whole blood, plasma and other biological fluids.

ELISA kit for Bovine Leptospiriosis

KTE10463-5platesof96wells 5 plates of 96 wells
EUR 2702.4
Description: Quantitative sandwich ELISA for measuring Bovine Leptospiriosis in samples from cell culture supernatants, serum, whole blood, plasma and other biological fluids.

ELISA kit for Bovine Leptospiriosis

KTE10463-96T 96T
EUR 686.4
Description: Quantitative sandwich ELISA for measuring Bovine Leptospiriosis in samples from cell culture supernatants, serum, whole blood, plasma and other biological fluids.

ELISA kit for Bovine Signal transducer and activator of transcription 5A

EK3921 96 tests
EUR 804
Description: Enzyme-linked immunosorbent assay kit for quantification of Bovine Signal transducer and activator of transcription 5A in samples from serum, plasma, tissue homogenates and other biological fluids.

ELISA kit for Bovine Signal transducer and activator of transcription 3

EK3929 96 tests
EUR 804
Description: Enzyme-linked immunosorbent assay kit for quantification of Bovine Signal transducer and activator of transcription 3 in samples from serum, plasma, tissue homogenates and other biological fluids.

ELISA kit for Bovine Cysteine and histidine-rich protein 1 (CYHR1)

KTE10381-48T 48T
EUR 424.8
Description: Quantitative sandwich ELISA for measuring Bovine Cysteine and histidine-rich protein 1 (CYHR1) in samples from cell culture supernatants, serum, whole blood, plasma and other biological fluids.

ELISA kit for Bovine Cysteine and histidine-rich protein 1 (CYHR1)

KTE10381-5platesof96wells 5 plates of 96 wells
EUR 2702.4
Description: Quantitative sandwich ELISA for measuring Bovine Cysteine and histidine-rich protein 1 (CYHR1) in samples from cell culture supernatants, serum, whole blood, plasma and other biological fluids.

ELISA kit for Bovine Cysteine and histidine-rich protein 1 (CYHR1)

KTE10381-96T 96T
EUR 686.4
Description: Quantitative sandwich ELISA for measuring Bovine Cysteine and histidine-rich protein 1 (CYHR1) in samples from cell culture supernatants, serum, whole blood, plasma and other biological fluids.

Dog Anti centriole and centrosome antibody ELISA kit

E08A0696-192T 192 tests
EUR 1524
Description: A competitive ELISA for quantitative measurement of Canine Anti centriole and centrosome antibody in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Dog Anti centriole and centrosome antibody ELISA kit

E08A0696-48 1 plate of 48 wells
EUR 624
Description: A competitive ELISA for quantitative measurement of Canine Anti centriole and centrosome antibody in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Dog Anti centriole and centrosome antibody ELISA kit

E08A0696-96 1 plate of 96 wells
EUR 822
Description: A competitive ELISA for quantitative measurement of Canine Anti centriole and centrosome antibody in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Sheep anti-bovine Thrombin polyclonal antibody

CABT-L410 500ug
EUR 877.2

Sheep anti-bovine Thrombin polyclonal antibody

CABT-L411 200ug
EUR 795.6

Sheep Anti Bovine Asialofetuin Polyclonal Antibody

CPBT-67285SB 1 ml
EUR 795.6

Sheep Anti Bovine Catalase Polyclonal Antibody

CPBT-67292SB 1 ml
EUR 795.6

Sheep Anti Bovine Iga Polyclonal Antibody

DPBT-67011SB 1 mg
EUR 696

Sheep Anti Bovine Igg Polyclonal Antibody

DPBT-67019SB 1 mg
EUR 696

Sheep Anti Bovine Igg1 Polyclonal Antibody

DPBT-67025SB 1 mg
EUR 696

Sheep Anti Bovine Igg2 Polyclonal Antibody

DPBT-67029SB 1 mg
EUR 696

Sheep Anti Bovine Igm Polyclonal Antibody

DPBT-67034SB 1 mg
EUR 696

ELISA kit for Bovine Albumin  Kit

KTE10443-48T 48T
EUR 424.8
Description: Quantitative sandwich ELISA for measuring Bovine Albumin  Kit in samples from cell culture supernatants, serum, whole blood, plasma and other biological fluids.

ELISA kit for Bovine Albumin  Kit

KTE10443-5platesof96wells 5 plates of 96 wells
EUR 2702.4
Description: Quantitative sandwich ELISA for measuring Bovine Albumin  Kit in samples from cell culture supernatants, serum, whole blood, plasma and other biological fluids.

ELISA kit for Bovine Albumin  Kit

KTE10443-96T 96T
EUR 686.4
Description: Quantitative sandwich ELISA for measuring Bovine Albumin  Kit in samples from cell culture supernatants, serum, whole blood, plasma and other biological fluids.

ELISA kit for Bovine Brucella abortus Antibody

KTE10446-48T 48T
EUR 424.8
Description: Quantitative sandwich ELISA for measuring Bovine Brucella abortus Antibody in samples from cell culture supernatants, serum, whole blood, plasma and other biological fluids.

ELISA kit for Bovine Brucella abortus Antibody

KTE10446-5platesof96wells 5 plates of 96 wells
EUR 2702.4
Description: Quantitative sandwich ELISA for measuring Bovine Brucella abortus Antibody in samples from cell culture supernatants, serum, whole blood, plasma and other biological fluids.

ELISA kit for Bovine Brucella abortus Antibody

KTE10446-96T 96T
EUR 686.4
Description: Quantitative sandwich ELISA for measuring Bovine Brucella abortus Antibody in samples from cell culture supernatants, serum, whole blood, plasma and other biological fluids.

ELISA kit for Dog Erythropoietin

EK1068 96 tests
EUR 804
Description: Enzyme-linked immunosorbent assay kit for quantification of Dog Erythropoietin in samples from serum, plasma, tissue homogenates and other biological fluids.

ELISA kit for Dog Fibronectin

EK1086 96 tests
EUR 865.2
Description: Enzyme-linked immunosorbent assay kit for quantification of Dog Fibronectin in samples from serum, plasma, tissue homogenates and other biological fluids.

ELISA kit for Dog Thrombomodulin

EK1879 96 tests
EUR 865.2
Description: Enzyme-linked immunosorbent assay kit for quantification of Dog Thrombomodulin in samples from serum, plasma, tissue homogenates and other biological fluids.

ELISA kit for Dog Procalcitonin

EK2126 96 tests
EUR 865.2
Description: Enzyme-linked immunosorbent assay kit for quantification of Dog Procalcitonin in samples from serum, plasma, tissue homogenates and other biological fluids.

ELISA kit for Dog Biglycan

EK2702 96 tests
EUR 865.2
Description: Enzyme-linked immunosorbent assay kit for quantification of Dog Biglycan in samples from serum, plasma, tissue homogenates and other biological fluids.

ELISA kit for Dog Clusterin

EK2901 96 tests
EUR 865.2
Description: Enzyme-linked immunosorbent assay kit for quantification of Dog Clusterin in samples from serum, plasma, tissue homogenates and other biological fluids.

It identified a decrease in the number of NAA, glutamate-glutamine complex, and an increase in the amount of choline and phosphoethanolamine relative to water and the amount of creatine in comparison with the reference interval in healthy control beagles. A further genetic testing confirmed LD. Abnormalities in 1HMRS despite the lack of change with conventional MRI identified in dogs with LD.